Vitamin K Deficiency: Laboratory Findings and Diagnosis

Overview of Vitamin K Deficiency

Vitamin K is essential for blood clotting and bone health. Its deficiency can lead to prolonged bleeding, easy bruising, and increased risk of fractures.

Causes of Vitamin K Deficiency

• Insufficient dietary intake
• Malabsorption disorders such as Crohn's disease
• Prolonged antibiotic use disrupting gut flora

Laboratory Findings

Key laboratory tests include:

• Prothrombin Time (PT): Elevated due to lack of clotting factors
• Activated Partial Thromboplastin Time (aPTT): May be normal or slightly prolonged
• Vitamin K levels: Can be measured via serum assays

Diagnosis and Management

Diagnosis is based on clinical symptoms and laboratory findings. Management includes dietary adjustments, supplementation, and addressing underlying conditions.

Prevention Strategies

• Balanced diet with leafy greens and fermented foods
• Avoid unnecessary antibiotic use
• Regular monitoring in at-risk populations