Bladder Cancer: Chemotherapy Treatment Modalities

Bladder cancer is a significant health concern that requires tailored treatment approaches. Chemotherapy is a crucial component in managing bladder cancer, whether as a primary treatment or in conjunction with surgery and radiation therapy.

Understanding Chemotherapy for Bladder Cancer

Chemotherapy involves the administration of anti-cancer drugs that target and destroy cancer cells. It can be systemic (affecting the whole body) or localized (delivered directly into the bladder).

Types of Chemotherapy

• Intravesical Chemotherapy: Used for non-muscle invasive bladder cancer; drugs are inserted directly into the bladder.
• Systemic Chemotherapy: Utilized for advanced bladder cancer; drugs circulate through the bloodstream to attack cancer cells.

Common Chemotherapy Drugs

Bladder cancer treatment typically involves drugs like:

• Cisplatin - A platinum-based agent that disrupts DNA synthesis in cancer cells.
• Gemcitabine - A nucleoside analog that inhibits cancer cell growth.
• Mitomycin C - Used in intravesical therapy to prevent tumor recurrence.

Side Effects and Management

Chemotherapy can lead to various side effects, including nausea, fatigue, and immune suppression. Proper management includes antiemetics, adequate hydration, and regular monitoring by healthcare providers.