Major types of hemoglobin and its derivatives
Physiological and pathological hemoglobin derivatives
Hemoglobin exists in physiological and pathological forms, influencing oxygen transport and overall health.
Major Types of Hemoglobin and Its Derivatives
Introduction
Hemoglobin is a crucial protein in red blood cells responsible for oxygen transport. It exists in various physiological and pathological forms, impacting health significantly.
Physiological Hemoglobin Derivatives
Oxyhemoglobin
Oxyhemoglobin (HbO2) is the oxygen-bound form of hemoglobin, essential for delivering oxygen to tissues.
Deoxyhemoglobin
Deoxyhemoglobin (Hb) is hemoglobin without oxygen, playing a vital role in oxygen exchange during respiration.
Pathological Hemoglobin Derivatives
Carboxyhemoglobin
Carboxyhemoglobin (HbCO) forms when hemoglobin binds with carbon monoxide, reducing oxygen transport efficiency.
Methemoglobin
Methemoglobin (MetHb) results from the oxidation of iron in hemoglobin, leading to decreased oxygen-binding capacity.
Sulfhemoglobin
Sulfhemoglobin (SulfHb) is an abnormal form caused by sulfur-containing drugs, affecting oxygen delivery.
Conclusion
Understanding hemoglobin and its derivatives is essential for diagnosing and managing various hematological disorders.
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