Toxicology of Thyroid Medications and Treatments

Overdose Effects and Symptoms of Levothyroxine and Liothyronine

Thyroid medications such as levothyroxine and liothyronine are essential for managing hypothyroidism and other thyroid-related conditions. However, overdose or improper use can lead to severe toxic effects.

Symptoms of Overdose

• Hyperthyroidism-like symptoms
• Palpitations and tachycardia
• Excessive sweating
• Agitation and nervousness
• Heat intolerance

Toxic Effects and Risk Factors

Excessive intake can result in thyrotoxicosis, affecting cardiovascular function and metabolic processes. Patients with pre-existing heart conditions are at greater risk.

Treatment and Management

Management includes supportive care, beta-blockers for cardiac symptoms, and activated charcoal in cases of acute overdose. Severe cases may require hospitalization.