Abortive Therapy for Migraine
NSAIDs and Their Role in Acute Migraine Management
NSAIDs serve as a cornerstone in abortive migraine therapy by inhibiting COX enzymes and reducing inflammation-associated pain.
Abortive Therapy for Migraine: NSAIDs and Their Role in Acute Migraine Management
Introduction
Migraines can be debilitating, affecting millions worldwide. While preventive therapies are available, abortive treatment is crucial for immediate relief. Nonsteroidal anti-inflammatory drugs (NSAIDs) play a pivotal role in managing acute migraine episodes.
Mechanism of Action
NSAIDs inhibit cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that contribute to inflammation and pain. This mechanism makes them effective in controlling migraine-associated pain.
Commonly Used NSAIDs
- Ibuprofen
- Naproxen
- Aspirin
- Diclofenac
Efficacy and Clinical Considerations
Clinical studies demonstrate that NSAIDs can reduce migraine intensity and duration when administered early. However, frequent use may lead to gastrointestinal discomfort or medication-overuse headaches.
Conclusion
NSAIDs remain an essential component of abortive migraine therapy. Consultation with a healthcare provider is recommended to determine the most appropriate treatment plan.