Principles and Mechanisms of Immunity

Innate Immunity: Overview and Key Components

Innate immunity is the body's first line of defense against pathogens. It is a non-specific immune response that acts immediately upon infection, providing rapid protection.

Key Components of Innate Immunity

• Physical Barriers: The skin and mucous membranes prevent pathogen entry.
• Cellular Defenses: Includes macrophages, neutrophils, and dendritic cells that identify and destroy pathogens.
• Chemical Mediators: Cytokines, complement proteins, and antimicrobial peptides help coordinate immune responses.
• Inflammatory Response: A critical mechanism that recruits immune cells to the site of infection.

Significance of Innate Immunity

Innate immunity acts as a foundation for adaptive immune responses, influencing long-term immunity and vaccination strategies.