Thrombosis, Infarction, and Aneurysm
Infarction: Mechanism, types (ischemic and hemorrhagic), effects on tissues and organs, and clinical relevance
Infarction, a condition arising from disrupted blood supply, leads to tissue necrosis. The two main types—ischemic and hemorrhagic—impact various organs, including the heart and brain.
Thrombosis, Infarction, and Aneurysm
Understanding Infarction
Infarction occurs due to the obstruction of blood supply, leading to tissue necrosis. It is primarily categorized into ischemic and hemorrhagic infarctions.
Mechanism of Infarction
- Blockage of arterial or venous blood flow
- Hypoxic injury leading to cellular death
- Subsequent inflammatory response
Types of Infarction
Ischemic Infarction
Results from a reduction in arterial supply, commonly due to thrombosis or embolism.
Hemorrhagic Infarction
Occurs when infarcted tissue undergoes secondary bleeding, often seen in venous obstruction.
Effects on Tissues and Organs
The impact varies based on the organ affected:
- Brain: Can lead to stroke, resulting in neurological deficits.
- Heart: Myocardial infarction, a critical condition affecting cardiac function.
- Lungs: Pulmonary infarction, causing respiratory distress.
- Intestines: Bowel infarction leading to severe abdominal pain.
Clinical Relevance
Recognizing infarction early is crucial for effective management. Treatment typically involves anticoagulant therapy, surgical interventions, and lifestyle modifications.
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