Thrombosis, Infarction, and Aneurysm
Infarction: Clinical significance and associated conditions
Infarction is the result of ischemic tissue necrosis due to vascular occlusion, leading to conditions such as myocardial infarction, strokes, and embolism-related complications.
Thrombosis, Infarction, and Aneurysm
Infarction: Clinical Significance and Associated Conditions
Infarction refers to tissue necrosis due to ischemia, typically caused by obstruction of blood supply. It plays a significant role in various pathological conditions, impacting multiple organ systems.
Clinical Significance
- Cardiac infarction (Myocardial infarction) - Result of coronary artery occlusion.
- Cerebral infarction - Leading cause of strokes.
- Pulmonary infarction - Associated with pulmonary embolism.
- Renal infarction - Often due to embolism or thrombus.
Pathophysiology
Infarction occurs when an artery supplying blood to an organ or tissue becomes obstructed, leading to oxygen deprivation and cell death. The severity of infarction depends on collateral circulation, duration of occlusion, and tissue vulnerability.
Associated Conditions
Several conditions contribute to infarction development, including:
- Atherosclerosis
- Thrombosis
- Embolism
- Vasospasm
Proper diagnosis and timely intervention are crucial for mitigating damage caused by infarction.
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