Indications for Liver Transplantation

Complications of Liver Disease Unresponsive to Medical Therapy

Liver transplantation is a life-saving procedure for individuals suffering from end-stage liver disease when conventional medical therapy fails to manage complications effectively.

Common Indications for Liver Transplantation

• Cirrhosis: Resulting from conditions such as hepatitis B/C, alcoholic liver disease, or nonalcoholic fatty liver disease.
• Acute Liver Failure: Due to viral hepatitis, drug toxicity, or Wilson's disease.
• Hepatocellular Carcinoma: When the tumor is confined to the liver and meets transplant criteria.
• Biliary Diseases: Primary sclerosing cholangitis or primary biliary cholangitis.
• Genetic or Metabolic Disorders: Such as Alpha-1 antitrypsin deficiency or familial amyloidosis.

Criteria for Transplant Eligibility

Patients undergo rigorous evaluations, including blood tests, imaging studies, and psychological assessments to ensure they can withstand the surgery and postoperative care.

Conclusion

Timely identification of liver disease complications is crucial for determining transplantation eligibility. A multidisciplinary approach improves patient outcomes and enhances long-term survival rates.