Hematological Indices and Peripheral Blood Smear Analysis

White Blood Cell Count and Differential

White blood cell count and differential analysis are vital for diagnosing infections, blood disorders, and immune-related conditions.

6/7/20253 min read34 views
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Understanding White Blood Cell Count and Differential

Hematological Indices and Peripheral Blood Smear Analysis

White Blood Cell Count and Differential

White blood cells (WBCs) play a crucial role in the body's immune defense system. Evaluating their count and differential helps in diagnosing various hematological conditions.

White Blood Cell Count

The WBC count measures the total number of white blood cells in a microliter of blood. Normal ranges vary but typically fall between 4,000 and 11,000 cells per microliter.

White Blood Cell Differential

A differential count identifies the percentage of different WBC types:

  • Neutrophils: Combat bacterial infections.
  • Lymphocytes: Integral to viral defense and immune regulation.
  • Monocytes: Involved in tissue repair and immune response.
  • Eosinophils: Associated with allergic reactions and parasitic infections.
  • Basophils: Play a role in inflammatory responses.

Peripheral Blood Smear Analysis

A peripheral blood smear examines the morphology of WBCs, red blood cells, and platelets. This helps detect abnormalities like anemia, infections, and hematological disorders.

Clinical Significance

Changes in WBC count and morphology can indicate infections, leukemia, autoimmune diseases, and bone marrow disorders. Early detection aids in effective management and treatment.

Tags

#Hematology#Blood Smear#White Blood Cell Count#Pathology

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