Etiology, Gross and Microscopic Features, and Complications of Abscess

Gross Morphological Characteristics of Abscess

An abscess is a localized collection of pus within tissue, commonly caused by infection. It presents as a swollen, red, and painful area, often accompanied by systemic symptoms like fever. The formation of an abscess follows a sequence of acute inflammation, leading to tissue destruction and suppuration.

Gross Features

• Encapsulated pus-filled cavity
• Surrounding edematous and inflamed tissue
• Central necrosis with liquefactive material

Microscopic Features

• Neutrophilic infiltration
• Fibrin deposition and necrotic debris
• Granulation tissue formation at the periphery

Complications

Untreated abscesses may lead to severe complications, including tissue necrosis, systemic infection, or abscess rupture. Early diagnosis and intervention are crucial to prevent progression.