Cutaneous Manifestations of Type 2 Diabetes

Diabetic Bullae – Clinical Characteristics and Treatment

Diabetic bullae, also known as bullosis diabeticorum, are spontaneous, fluid-filled blisters that occur in individuals with diabetes, particularly in those with long-standing disease. These blisters are typically painless and appear on the extremities, such as the hands and feet.

Clinical Features

• Rapid onset of blisters, often without preceding trauma
• Clear, sterile fluid within the bullae
• Non-inflammatory presentation, usually without surrounding erythema
• Common sites include the lower legs, feet, and hands

Pathogenesis

The exact mechanism of diabetic bullae formation is not completely understood. However, it is believed to be related to microvascular complications, neuropathy, and structural abnormalities in the skin due to chronic hyperglycemia.

Management and Treatment

Diabetic bullae typically resolve on their own within a few weeks. However, proper care is necessary to prevent secondary infection:

• Avoid puncturing the blisters unless medically necessary
• Maintain strict glycemic control to prevent recurrence
• Apply antiseptic dressings if blisters rupture
• Seek medical attention if signs of infection arise