Clinical Manifestations of Acute HIV Seroconversion

Oropharyngeal Symptoms: Sore Throat and Lymphadenopathy

Acute HIV seroconversion refers to the period when the body first develops antibodies against HIV. This phase can present with various symptoms, including fever, rash, and oropharyngeal manifestations like sore throat and lymphadenopathy.

Understanding Sore Throat in Acute HIV Seroconversion

Sore throat, or pharyngitis, is one of the early signs of acute HIV infection. It results from the immune system's initial response to the virus, leading to inflammation in the throat. This symptom may be accompanied by difficulty swallowing and redness.

Lymphadenopathy: Swollen Lymph Nodes

Lymphadenopathy, or swollen lymph nodes, is a critical sign of immune activation during acute HIV infection. The cervical, axillary, and inguinal lymph nodes may become enlarged and tender due to rapid viral replication.

Diagnosis and Clinical Implications

• HIV-specific antibody tests confirm seroconversion.
• Patients with symptoms like pharyngitis and lymphadenopathy should undergo HIV screening.
• Early detection allows timely intervention, improving prognosis.

Management and Care

While symptomatic relief can be achieved with hydration and pain relievers, HIV-specific antiretroviral therapy is crucial to controlling the infection and reducing viral load.