Vitamin A Deficiency and Excess: Causes, Clinical Features, Diagnosis, and Management
Clinical Features of Vitamin A Excess
Vitamin A excess, or hypervitaminosis A, can cause acute and chronic toxicity with severe health consequences. Proper diagnosis and management are crucial to mitigate risks.
6/6/2025• 5 min read• 42 views
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Vitamin A Excess: Clinical Features, Diagnosis, and Management
Vitamin A is an essential fat-soluble vitamin crucial for vision, immune function, and cellular health. However, excessive intake can lead to toxicity, known as hypervitaminosis A. Below, we outline the clinical features, diagnosis, and management of vitamin A excess.
Clinical Features of Vitamin A Excess
Acute Toxicity
- Nausea and vomiting
- Dizziness
- Headache
- Blurred vision
Chronic Toxicity
- Skin dryness and peeling
- Hepatotoxicity
- Increased intracranial pressure
- Bone demineralization and fractures
- Teratogenic effects in pregnancy
Diagnosis
Diagnosis is based on clinical symptoms and serum retinol levels. Imaging and liver function tests may be required for chronic cases.
Management
- Cease excessive vitamin A intake
- Supportive care for acute toxicity
- Monitor liver function and bone health
- Pregnancy counseling for teratogenic risks
Tags
#Vitamin A Toxicity#Hypervitaminosis A#Biochemistry#Medical Diagnosis#Nutrition
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