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Classification of Hemolytic Anemia

Diagnostic Approaches

Hemolytic anemia is classified into intrinsic and extrinsic types based on underlying causes. Accurate diagnosis is essential for effective management.

6/7/20255 min read36 views
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Classification & Diagnosis of Hemolytic Anemia

Classification of Hemolytic Anemia

Introduction

Hemolytic anemia is a condition characterized by the premature destruction of red blood cells (RBCs), leading to anemia. It can be classified based on its underlying causes, which include intrinsic and extrinsic factors.

Classification

Intrinsic Hemolytic Anemia

  • Hereditary Spherocytosis
  • Sickle Cell Disease
  • G6PD Deficiency
  • Thalassemia

Extrinsic Hemolytic Anemia

  • Autoimmune Hemolytic Anemia
  • Microangiopathic Hemolytic Anemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)

Diagnostic Approaches

Laboratory Investigations

  • Complete Blood Count (CBC)
  • Peripheral Blood Smear
  • Coombs Test
  • Lactate Dehydrogenase (LDH) Levels

Imaging & Bone Marrow Analysis

Additional diagnostic methods include ultrasound for splenomegaly and bone marrow examination for assessing erythropoiesis.

Conclusion

Timely and accurate diagnosis of hemolytic anemia is crucial for effective treatment and management. Proper classification aids in determining the appropriate therapeutic interventions.

Tags

#Hemolytic Anemia#Autoimmune Hemolytic Anemia#Pathology#G6PD Deficiency#Sickle Cell Disease

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